Dr. Brooke E. Christian

Dr. Brooke E. Christian

christianbe@appstate.edu 

Dr. Christian graduated from Appalachian State University in 2005 and received her Ph.D. in Biological Chemistry in 2010 from the University of North Carolina at Chapel Hill. Her graduate work in the research group of Dr. Linda Spremulli focused on mechanisms of translation initiation in mammalian mitochondria. Brooke did her postdoctoral work at Yale University as an NIH postdoctoral fellow in the laboratory of Dr. Gerald Shadel where she studied the contribution of mitochondrial reactive oxygen species to the neurodegenerative disease Ataxia-Telangiectasia. Dr. Christian joined the department of chemistry at Appalachian State University in2015 and teaches biochemistry and biochemistry lab. 

Current research projects in the Christian lab are focused on mitochondrial reactive oxygen species and the roles they play in assembly of oxidative phosphorylation complexes and in adipocyte differentiation. Techniques used in the Christian lab include tissue culture, western blotting, qPCR, PAGE (denaturing/SDS and blue native), shRNA knockdown of genes of interest, immunofluorescence, and subcellular fractionation.


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