Dr. Megen A. Culpepper

Dr. Culpepper received her Ph.D. in Analytical Chemistry in 2009 from the University of Kansas working in the research groups of Dr. Julian Limburg and Dr. Emily E. Scott. Her graduate work focused on determining the structure and function of a prolyl 4-hydroxylase-like protein involved in collagen production. After graduate school, Dr. Culpepper moved to Northwestern University to the laboratory of Dr. Amy C. Rosenzweig where she was awarded an NIH postdoctoral fellowship studying biological methane oxidation by the membrane protein particulate methane monooxygenase. Dr. Culpepper joined the department of chemistry at Appalachian State University in 2014 and teaches classes in Analytical, Biochemistry and Introductory Chemistry.

Current research projects in the Culpepper lab utilize interdisciplinary techniques encompassing biochemistry, molecular biology, and analytical chemistry. Research projects investigate the protein structure and biochemical function of enzymes involved in the global sulfur cycle. Namely, an enzyme responsible for the degradation of dimethyl sulfide (DMS), the major contributing volatile organic sulfur compound (VOSC) in our atmosphere implicated in climate regulation. Research students learn protein expression and purification as well as biochemical characterization using analytical instrumentation. We utilize facilities at Wake Forest University for three-dimensional protein structure determination all towards understanding how structure dictates chemical mechanism. 

Title: Assistant Professor
Department: Chemistry

Email address: Email me

Phone: (828) 262-7069

Office address
357 GWH