Dr. Jennifer Cecile

Dr. Jennifer Perry Cecile

cecilejp@appstate.edu

Dr. Cecile received a Ph.D. in Chemistry in 2003 from Duke University working in the research group of Dr. John Simon. Her graduate research used fluorescence spectroscopy to characterize photophysical properties of the fungal metabolite ochratoxin a and to examine the binding of various ligands to the blood protein human serum albumin. After graduate school, Dr. Cecile completed postdoctoral research at the National Institute of Environmental Health Sciences in the Research Triangle Park, NC. During that time, she studied structure/function interactions of negatively charged xenobiotics and a family of proteins named the organic anion transporters (OATs). She also became interested in the effects of genetic variability and regulation on OAT protein expression and function.

Dr. Cecile joined the chemistry department at Appalachian State University in 2007 teaching introductory and physical chemistry courses. Currently, her research involves techniques from biochemistry, biophysical chemistry and biology.  Her research projects include implementing a nematode model system to study xenobiotic transport by OATs, building models of OAT structure to analyze amino acids that contribute to OAT function, and observing functional consequences of genetic splice variants and single nucleotide polymorphisms on OAT protein expression and regulation.

 

 


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